Placenta Related Studies and Articles.

Traditional Chinese Medicine has used the placenta for thousands of years, I have prepared over 200 placentas now in my two and a half years of offering this service and my clients have benefited tremendously.  For those of you that need a bit more, here you go.

Placenta as a Lactagogon– Study on placenta and increased milk production
Soykova-Pachnerova E, et. al.(1954). Gynaecologia 138(6):617-627.

Placentophagia- A Biobehavioral Enigma
MARK B. KRISTAL, Received 2 February 1980. Neuroscience & Biohehavioral Reviews, Vol. 4, pp. 141–150.

Wound Healing Activity of Human Placental Extract in Rats
Acta Pharmacol Sin, 22 Dec 2001
Finding human placental extract has potent power of inducing collagenous growth indicating its proficiency in wound healing.

Effects of placentophagy on serum prolactin and progesterone concentrations in rats after parturition or superovulation
Blank MS, Friesen HG.: J Reprod Fertil. 1980 Nov;60(2):273-8.

Enhancement of opioid-mediated analgesia: A solution to the enigma of placentophagia
Mark B. Kristal
Department of Psychology, State University of New York at Buffalo, Buffalo, NY 14260, USA
Received 4 January 1991.

Placenta and Pain Relief
Jean M. DiPirro*, Mark B. Kristal

Hypothalamic corticotropin-releasing hormone suppression during the postpartum period: implications for the increase in psychiatric manifestations at this time – Study showing low CRH Hormone levels post-birth – CRH (stress reducer hormone – found in high levels in the placenta)
Journal of Clinical Endocrinology & Metabolism, Vol 81, 1912-1917, Copyright © 1996 by Endocrine Society

Maternal Iron Deficiency Anemia Affects Postpartum Emotions and Cognition
John L. Beard,2 Michael K. Hendricks,* Eva M. Perez,* Laura E. Murray-Kolb, Astrid Berg,*
Lynne Vernon-Feagans,† James Irlam,* Washiefa Isaacs,* Alan Sive,* and Mark Tomlinson*
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802; *School of
Child and Adolescent Health, University of Cape Town, Cape Town, South Africa; and †School of Education,
University of North Carolina, Chapel Hill, NC 27599

Have we forgotten the significance of postpartum iron deficiency?
Lisa M. Bodnar, PhD, MPH, RD,a,* Mary E. Cogswell, DrPH, RN,b
Thad McDonald, MDc

The Impact of Fatigue on the Development of Postpartum Depression
Elizabeth J. Corwin, Jean Brownstead, Nichole Barton,
Starlet Heckard, and Karen Morin

Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial
F Verdon, general practitioner1, B Burnand, senior lecturer2, C-L Fallab Stubi, pharmacist3, C Bonard, general practitioner1, M
Graff, general practitioner1, A Michaud, general practitioner1, T Bischoff, general practitioner1, M de Vevey, general practitioner1,
J-P Studer, general practitioner1, L Herzig, general practitioner1, C Chapuis, general practitioner1, J Tissot, general practitioner1,
A Pécoud, professor3, B Favrat, consultant of internal medicine3
BMJ  2003;326:1124 (24 May), doi:10.1136/bmj.326.7399.1124

The Bridge of Life: Options for Placentas
Written by British midwife Kelly Graff; Published by Midwifery Today 2008

Placentophagia: Benefits of Eating the Placenta
Published June 28, 2007
by:Amy Weekley

Placenta consumption
Written for BabyCenter Singapore Approved by the BabyCenter Medical Advisory Board

Medicinal Uses of the Placenta
The gentlebirth.org website is provided courtesy of
Ronnie Falcao, LM MS, a homebirth midwife in Mountain View, CA

Placenta: The Gift of Life

The Tree of Life
Hollywood Birth Centre Newsletter August 2009

The Amazing Placenta
By Robin Elise Weiss, LCCE, About.com Guide

I’m Going to Eat My Placenta
posted by Kiri Westby Jun 28, 2010 5:08 pm

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Postpartum Depression:  Exploring the Signs, the Causes, the Remedies, and Theories in Natural Prevention

A Presentation by Alexandra Orchard

SOURCES:

I used the following sources to find most of the information I presented:

1. Ford, G.  Listening To Your Hormones.  Rocklin, CA: Prima Publishing; 1997 (pages 30-31, 38-39, 61-81, 88-89, 106-107, 114-115, 154-157, 164-165, 170-191, 210-213, 305-319, and 384-385)
2. Bennett, S. S., & Indman, P. ,. (2006). Beyond The Blues. San Jose, CA: Moodswings Press.  Pages 32 and 34
3. KRISTAL, M.B. Enhancement of opioid-mediated analgesia: A solution to the enigma of placentophagia. NEUROSCI BIOBEHAV REV 15(3) 425-435, 1991
4. KRISTAL, M.B.  Placentophagia:  A Biobehavioral enigma  Neuroscience & Biohehavioral Reviews, Vol. 4, pp. 141–150.
5. Jean M. DiPirro, Mark B. Kristal, Placenta ingestion by rats enhances delta- and kappa-opioid antinociception, but suppresses mu-opioid antinociception Brain Research 1014 (2004) 22–33
6. Rice J. Medical Terminology with Human Anatomy. 5th ed. Upper Saddle River, NJ: Pearson Education, Inc.; 2005 pages 352-363)
7. Frye A. Holistic Midwifery, Vol 1.Portland, OR: Labrys Press; 2006 (p 188-198)
8. http://www.med.yale.edu/obgyn/kliman/placenta/articles/Plac%20Hormones.html
9. http://www.vivo.colostate.edu/hbooks/pathphys/reprod/placenta/endocrine.html

10.  http://books.google.com/books?id=Eh2HrXYqJJYC&pg=PA228&dq=Hormone+in+placental+tissue&cd=5#v=onepage&q=Hormone%20in%20placental%20tissue&f=false Normal human tissue and cell culture, Volume 2 By Curtis C. Harris, Benjamin Franklin Trump, Gary D. Stoner  PAGE 236

11.  http://www.ncbi.nlm.nih.gov/pubmed/13129686 Placenta. 2003 Sep-Oct;24(8-9):882-94.Trophoblast viability in perfused term placental tissue and explant cultures limited to 7-24 hours. Di Santo S, Malek A, Sager R, Andres AC, Schneider H. Universitäts-Frauenklinik Inselspital, Effingerstrasse 102, CH-3010 Berne, Switzerland.

12.  http://www.ncbi.nlm.nih.gov/pubmed/6609066 Endocrinol Exp. 1984 Mar;18(1):35-41. Immunoreactive oxytocin in human placental tissue. Nakazawa K, Makino T, Nagai T, Suzuki H, Iizuka R.

13.  http://www.ncbi.nlm.nih.gov/pubmed/9290148 Placenta. 1997 Sep;18(7):535-40.Thyroid hormone efflux from placental tissue is not stimulated during cell volume regulation. Mitchell AM, Manley SW, Mortimer RH. Conjoint Endocrine Laboratory, Royal Brisbane Hospital, Queensland, Australia.

14.  http://books.google.com/books?id=NR1Pcv4Dxs4C&pg=PA147&lpg=PA147&dq=thyroid+hormones+found+in+placental+tissue&source=bl&ots=HzPMSNEbVU&sig=3vQU3f54UtNix5odnF3e5VTavz0&hl=en&ei=cr9lS_uyCIXoM6q8veoG&sa=X&oi=book_result&ct=result&resnum=2&ved=0CA0Q6AEwAQ#v=onepage&q=thyroid%20hormones%20found%20in%20placental%20tissue&f=false Pathology of the human placenta By Kurt Benirschke, Peter Kaufmann  4^th ed.Springer-Verlag New York, Inc.; New York.  page 147

15.  http://www.eje-online.org/cgi/reprint/147/6/785.pdf CLINICAL STUDY Pregnancy-associated and placental proteins in the placental tissue of normal pregnant women and patients with pre-eclampsia at term

Nick A Bersinger, Nigel Groome1 and Shanthi Muttukrishna2

Department of Obstetrics and Gynaecology, University of Berne, Berne, Switzerland, 1School of Biological and Molecular Sciences,

Oxford Brookes University, Oxford, UK and 2Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK

(Correspondence should be addressed to N A Bersinger, Reproductive and Perinatal Medicine Research Laboratory, Inselspital G3-855 KKL, Berne,

CH-3010, Switzerland; Email: nick.bersinger@dkf2.unibe.ch)

(Shanthi Muttukrishna is currently at Department of Obstetrics and Gynaecology, University College London, Royal Free–UCL Medical School,

London WC1E 6HX, UK)

16.  http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.ph.43.030181.001115

Annual Review of Physiology
Vol. 43: 163-188 (Volume publication date October 1981)
(doi:10.1146/annurev.ph.43.030181.001115)

Endocrine Physiology of the Placenta

E R Simpson, and P C MacDonald

17.  http://ajpregu.physiology.org/cgi/content/full/287/4/R894 Influence of gestational age and fetal iron status on IRP activity and iron transporter protein expression in third-trimester human placenta  Jenni Bradley,¹ Elizabeth A. Leibold,² Z. Leah Harris,³ Jane D. Wobken,¹ Stephen Clarke,⁴ Kimberly B. Zumbrennen,² Richard S. Eisenstein,⁴ andMichael K. Georgieff¹Am J Physiol Regul Integr Comp Physiol 287: R894-R901, 2004. First published June 3, 2004; doi:10.1152/ajpregu.00525.2003

18.  http://www.courseweb.uottawa.ca/medicine-histology/english/Reproduction/Placenta/Default.htm

19.  http://www.med.yale.edu/obgyn/kilman/placenta/articles/Plac%20Hormones.html

20.  Baby Blues-postpartum depression attributed to low levels of CRH after placenta is gone-brief article.  Discover, Dec, 1995

21.  BMJ  2003;326:1124 (24 May), doi:10.1136/bmj.326.7399.1124 http://www.bmj.com/cgi/content/full/326/7399/1124 © 2005 The American Society for Nutritional Sciences J. Nutr. 135:267-272, February 2005 http://jn.nutrition.org/cgi/content/full/135/2/267

22.  Elizabeth J. Corwin, Jean Brownstead, Nichole Barton, Starlet Heckard, Karen Morin (2005) The Impact of Fatigue on the Development of Postpartum Depression Journal of Obstetric, Gynecologic, & Neonatal Nursing 34 (5) , 577–586 doi:10.1177/0884217505279997

23.  Soykova-Pachnerova,E.  “Placenta as Lactagogon” Gynecologia:  International monthly review of obstetrics and gynecology. 1954, pages 617-27

24.  http://www.premarin.org/estrogen.html